兒童青少年憂鬱症與重覆經顱磁刺激 (rTMS)
Paul E Croarkin與Frank P MacMaster教授(Croarkin and MacMaster, 2019) 回顧10篇青少年憂鬱症使用重覆經顱磁刺激 (rTMS)的研究。腦區主要在DLPFC，七個試驗使用10Hz，Le et al 團隊使用iTBS and cTBS。
Paul E Croarkin團隊發表雙盲隨機試驗(Croarkin et al., 2021)，招募103位青少年憂鬱症(48為治療組接受NeuroStar TMS，55為對照組)，為期六周30次治療。六周後有實驗組有反應為41.7%。Response rates were 41.7% in the active group and 36.4% in the sham group (P = 0.6). Remission rates were 29.2% in the active group and 29.0% in the sham group (P = 0.95).
參考文獻
Croarkin PE, Elmaadawi AZ, Aaronson ST, et al. (2021) Left prefrontal transcranial magnetic stimulation for treatment-resistant depression in adolescents: a double-blind, randomized, sham-controlled trial. Neuropsychopharmacology 46: 462-469.
Croarkin PE and MacMaster FP. (2019) Transcranial Magnetic Stimulation for Adolescent Depression. Child Adolesc Psychiatr Clin N Am 28: 33-43.
